Brain cancer cases

Case 1: Oligodendroglioma-glioblastoma Pathology

Name: Sirvart Doganian de Topalian
Age: 74 years old
Country: Brazil
Reason of consultation:
Brain tumor
Personal antecedents:
No personal antecedents to remark.
Family antecedents:
No family antecedents to remark.
Present disease antecedents:
On 09/02/1999: she has a cranial CAT done which shows as a conclusion a left frontal expansive lesion. Front-parietal expansive process, whose nature is to be clarified.
On 06/15/1999: she has a magnetic nuclear resonance done which shows left frontal expansive lesion that presents heterogenic aspect and irregular contours, observing hyper-signal areas in T1 and hypo-signal in T2. Suggesting blood component, signs of peri-lesional edema, there is expansive effect characterized by erasing of the adjacent lines and compression of the left lateral ventricle, with slight deviation of the middle line structures. This lesion measures approximately 4 cm. Of diameter. The conclusion is that the magnetic nuclear resonance aspect is of a left frontal blastomatose process of probable glial origin.
09/26/1999: She has another cranial CAT done that does not show significant changes considering the previous ones.
On 09/28/1999: By per-surgery biopsy is diagnosed primary mixed brain malignant neoplasy, oligodendroglioma-glioblastoma.
On 12/23/1999: A new cranial computerized tomography is done which shows: Signs of left frontal craniotomy, hypo-atenuating area in left frontal area is observed, in the borders of the craniotomy, which after the intra-venous injection of yode contrast, produces annular highlighting. Recidivism? Accentuation of cortical lines and fissures and cerebella lines. Centro medial structures without deviation relating the middle line. Slight expansion of the supra-tentorial ventricular system. Post-surgery control.
On 01/17/2000: A cranial magnetic resonance is done, conclusion: left frontal lesion suggesting glial originated lesion, in relation to the previous exam of 09/15/1999 a reduction of the dimensions of the described lesion is observed.
Observation: Signs of right maxillary sinusopathy and bilateral sphenoidal.
On 05/26/2000: Encephalic magnetic resonance, conclusion: post-surgery control of left frontal neoplasy, post-surgery alterations with blood rests occupying the surgery remotion cavity. Extended alteration of the sign of the white substance of the brain hemispheres, of unspecific nature, maybe representing gliosis, de-mielinization associated to micro-angiopathies, not being possible to exclude post-actinic leuco-encephalopathy if the patient underwent radiotherapy. Gliosis focuses and/or ischemic lagoons, and/or peri-vascular spaces extended in lentiform nucleus, caudated, internal capsules and sub-insular regions. Cortico-subcortical encephalic volumetric reduction.
Disease evolution:
She begins to take GREEN SAP drops at a dosage of 40 drops, 6 times per day in August, 2000.
On 08/31/2000: An encephalic magnetic resonance is done which shows, conclusion: post-surgery control, blood rests occupying surgery remotion area with smaller dimensions in relation to the last exam with no evidences of local recidivism.
The rest of the findings did not alter significantly from the last study.
On 01/30/2001: An encephalic magnetic resonance is done which shows: conclusions: Post-surgery control exam of left frontal neoplasy, in relation to the previous exam (from 08/31/2000) it is noted a reduction of the dimensions of the blood content and the contrast associated of the medium left frontal lesion and in correspondence to the surgery layer. Slight increase of the extension of the diffuse signal alteration in the white substance of the brain hemispheres, of unspecific significance. If there has been radiotherapy post-actinic leuco-encephalopathy has to be the first diagnose consideration.
On 04/27/2001: Encephalic magnetic resonance, in relation to the previous exam of 01/30/2001, there are evidences of partial absorption of the blood rests, which are situated in the surgery layer, as well as of the associated residual contrast; with other findings practically unaltered.
No evidences of local neoplasic recidives have aroused.
On 09/04/2001: Cranial magnetic resonance, conclusions: Analysis: Signs of left frontal craniotomy, slight expansion of the supra-tentorial ventricles, without hypertensive characteristics, slight expansion of the IV ventricle, slight accentuation of cortical lines and fissures and of the basal cisterns. Excepting for lines in the left frontal region, which are partially fainted. Diffuse hypersignal in T2, and Flair in the white substance bilaterally compatible with leuko-encephalopathy.
Presence of magnetic susceptible articles in the craniotomy area which may give partly the adjacent structures image.
On 08/14/2002: Cranial magnetic resonance, showed: left frontal craniotomy, with presence of slight irregular areas of post-contrast highlighting, besides the surgery layer, less evident in the present study.
Magnetic susceptible artifacts adjacent to the craniotomy. Peri-vascular spaces extended. There persist extended areas of signal alteration, characterized by a high sign in T2 and Flair that does not present post-contrast highlighting, compromising the white substance of both brain hemispheres. Suggesting post-actinic alterations. The rest of the encephalic parenchyma with normal sign intensities. Crane-vertebral transition without abnormalities. Extended cortical lines. Big Silvian caesuras and basal cisterns. Dilatation of the supra-tentorial ventricular system, IV ventricle with normal form and dimensions.
Comparatively to the previous exam, reduction of the extension and intensity of the signals of the post-contrast highlighting areas was observed adjacent to the left frontal craniotomy.
Cranial magnetic resonance was made on 01/02/2003, which shows: left frontal post-surgery status. The comparative analysis of the present exam to that of the previous one no significant alterations are observed. Irregular contrast focus in the left frontal white substance which can correspond to a gliosis focus but does not discard recidivism signs. Increase of the encephalic liquid spaces. Signs of micro-leuko-angiopathy, peri-ventricular and in semi-oval centers.
We must remark that the patient received in all this period GREEN SAP drops as medicament, finding herself as it arises from the imagenologic results, stable since 2 years and a half ago with the intake of the medicament. Although the tumor extirpation was performed we think that this therapy alone does not justify the excellent evolution she had afterwards, reason why we consider her asymptomatic in clinic cure, receiving maintenance dosage of the medicament.
Conclusions:

It is about a patient of 74 years old at present, with a brain malignant neoplasy of ominous prognosis. This neoplasy was extirpated, turning out to be a oligodendroglioma-glioblastoma, the patient in the 2000 begins to take the medicament, maintaining unchanged the imagenology and with a tendency to reduction. GREEN SAP evidently acted crossing the hemato-encephalic barrier as we stated in the central nervous system GREEN SAP anti-tumor action. This appears evident by the excellent result achieved as in the other cases already referred. This is why that a direct GREEN SAP action on the tumor is observed, although before we did not have the experience we nowadays have and was stated that GREEN SAP could not cross the hemato-encephalic barrier as well as many other medicaments.
Nowadays, with the acquired experience and the results achieved by the patients, we firmly think that GREEN SAP has a very well deserved position in the treatment of the Central Nervous System tumors, obtaining remissions, stabilizations and clinic cures. It is remarkable that no endo-cranial hypertension syndrome has produced, and this would be related to the mass effect taken away by the surgery, but also to the anti-inflammatory and stabilization effect of GREEN SAP.
This is a case that fills us with proud. The use of our medicament, which has already been proved by time and the empiric experience, has led a very difficult prognosis patient, even with the more modern conventional techniques, to a state of health. At the present moment she is in cure and can perform the tasks that other people of her age develop. GREEN SAP is a medicament of proven efficacy, even in so dangerous diseases and recommendable in oncology pathology. We can affirm this medicament is a so fortunate finding from the medical point of view that enables us to have such rewards as the one offered by this patient. This medicament is not an improvisation and hundreds of cases all around the world testify so. It creates hope where there is hopelessness, creates strength where the body and the soul weak and from the medical point of view achieves a percentage of cure that plenty justifies what we previously said.